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1

Flavonoids Regulate Eag1 Channels

Carlson, Anne E., Brelidze, Tinatin I., Davies, Douglas R., Zagotta, William N.

Journal:

Biophysical Journal

Year:

2010

Language:

english

File:

PDF, 34 KB

english, 2010

2

Exploring Ligand Regulation of Ion Channels in the EAG Family

Brelidze, Tinatin I., Zagotta, William N.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 38 KB

english, 2011

3

Structure of the C-Terminal Region of a KCNH Channel

Brelidze, Tinatin I., Carlson, Anne E., Sankaran, Banumathi, Zagotta, William N.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 37 KB

english, 2012

4

Fisetin Regulation of HCN2 and Eag1 Channels Reveals Conserved Gating Mechanisms

Carlson, Anne E., Brelidze, Tinatin I., Zagotta, William N.

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 40 KB

english, 2012

5

Structure of the C-Terminal Region of an ERG Channel and Functional Implications for Long-QT Syndrome

Brelidze, Tinatin I., DiMaio, Frank, Trudeau, Matthew C., Zagotta, William N.

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

6

Structure of the carboxy-terminal region of a KCNH channel

Brelidze, Tinatin I., Carlson, Anne E., Sankaran, Banumathi, Zagotta, William N.

Journal:

Year:

2012

Language:

english

File:

PDF, 956 KB

english, 2012

7

Investigating Ligand Binding to HCN Channels by Surface Plasmon Resonance

Tiwari, Purushottam, Üren, Aykut, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2017

Language:

english

File:

PDF, 47 KB

english, 2017

8

N- and C-terminal interactions in KCNH channels: The spotlight on the intrinsic ligand

Brelidze, Tinatin I.

Journal:

The Journal of General Physiology

Year:

2019

File:

PDF, 814 KB

2019

9

The Role of HCN Domain in the Function of HCN Channels

Wang, Zejun, Hayoz, Sebastien, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 44 KB

english, 2019

10

The Role of HCN Domain in the Function of HCN Channels

Wang, Zejun, Hayoz, Sebastien, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2019

File:

PDF, 44 KB

2019

11

Identification of undecylenic acid as EAG channel inhibitor using surface plasmon resonance-based screen of KCNH channels

Wang, Ze-Jun, Tiwari, Purushottam B., Üren, Aykut, Brelidze, Tinatin I.

Journal:

BMC Pharmacology and Toxicology

Year:

2019

Language:

english

File:

PDF, 2.05 MB

english, 2019

12

Investigating Cyclic Dinucleotide Binding to HCN Channels by Surface Plasmon Resonance and Isothermal Calorimetry

Hayoz, Sebastien, Tiwari, Purushottam B., Piszczek, Grzegorz, Üren, Aykut, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2018

File:

PDF, 39 KB

2018

13

Identifying Novel KCNH Channel Ligands with Surface Plasmon Resonance Method

Tiwari, Purushottam, Uren, Aykut, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2019

Language:

english

File:

PDF, 41 KB

english, 2019

14

Identifying Novel KCNH Channel Ligands with Surface Plasmon Resonance Method

Tiwari, Purushottam, Uren, Aykut, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2019

File:

PDF, 41 KB

2019

15

Increased Smooth Muscle Kv11.1 Channel Expression in Pulmonary Hypertension and Protective Role of Kv11.1 Channel Blocker Dofetilide

Shults, Nataliia V., Rybka, Vladyslava, Suzuki, Yuichiro J., Brelidze, Tinatin I.

Journal:

The American Journal of Pathology

Year:

2020

File:

PDF, 3.98 MB

2020

16

Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity

Wang, Ze-Jun, Soohoo, Stephanie M, Tiwari, Purushottam B, Piszczek, Grzegorz, Brelidze, Tinatin I

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 9.79 MB

2020

17

The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms

Wang, Ze-Jun, Blanco, Ismary, Hayoz, Sebastien, Brelidze, Tinatin I

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 8.15 MB

2020

18

EAG Channel PAS Domain Binder Inhibits Currents from EAG Channels and Decreases Tumor Growth in Zebrafish Xenograft Model

Wang, Ze-Jun, Kamgar-Dayhoff, Pareesa, Tiwari, Purushottam B., Glasgow, Eric, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 46 KB

2020

19

HCN Domain is Necessary for Surface Expression of HCN Channels

Wang, Zejun, Blanco, Ismary, Brelidze, Tinatin I.

Journal:

Biophysical Journal

Year:

2020

File:

PDF, 44 KB

2020